Anti-STIMATE Polyclonal Antibody - HRP
Cat: K113510P - HRP
Summary:
| 【Product name】：Anti-STIMATE Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：375346 | 【Swiss Prot】：Q86TL2 |
| 【Species reactivity】：Human;Mouse;Rat | |
| 【Tested applications】：WB IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human STIMATE | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Acts as a regulator of store-operated Ca2+ entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574).SOCE is a Ca2+ influx following depletion of intracellular Ca2+ stores (PubMed:26322679).Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679).Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574).Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).
Verified picture: