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Anti-STIMATE Polyclonal Antibody - SAlexa Fluor 660
Cat: K113510P - SAlexa Fluor 660
Summary:
【Product name】:Anti-STIMATE Polyclonal Antibody - SAlexa Fluor 660 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:375346 【Swiss Prot】:Q86TL2
【Species reactivity】:Human;Mouse;Rat
【Tested applications】:WB IHC
【Immunogen】:A synthetic peptide of human STIMATE
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Acts as a regulator of store-operated Ca2+ entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574).SOCE is a Ca2+ influx following depletion of intracellular Ca2+ stores (PubMed:26322679).Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679).Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574).Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).
Verified picture: