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Anti-Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) Polyclonal Antibody
Cat: K010452P
Summary:
【Product name】:Anti-Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5594/5595 【Swiss Prot】:P28482/P27361
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB
【Immunogen】:A synthetic peptide of human Phospho-ERK1(T202/Y204)+ERK2(T185/Y187)
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
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