Anti-Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) Polyclonal Antibody - HRP
Cat: K010452P - HRP
Summary:
| 【Product name】：Anti-Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5594/5595 | 【Swiss Prot】：P28482/P27361 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Phospho-ERK1(T202/Y204)+ERK2(T185/Y187) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
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