下载
Anti-ATP6V0C Polyclonal Antibody - SAlexa Fluor 633
Cat: K113651P - SAlexa Fluor 633
Summary:
【Product name】:Anti-ATP6V0C Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:527 【Swiss Prot】:P27449
【Observed】:19kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:A synthetic peptide of human ATP6V0C
【Public Immunogen Range】:100-150/155aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c, and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17.
Verified picture: