Anti-SYTL2 Polyclonal Antibody - Cy5.5
Cat: K113769P - Cy5.5
Summary:
| 【Product name】：Anti-SYTL2 Polyclonal Antibody - Cy5.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：54843 | 【Swiss Prot】：Q9HCH5 |
| 【Species reactivity】：Human;Mouse | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human SYTL2 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca2+ while binding to PIP2 is Ca2+ insensitive.
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