Anti-MAGC2/MAGC1 Polyclonal Antibody
Cat: K113822P
Summary:
| 【Product name】：Anti-MAGC2/MAGC1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：51438/9947 | 【Swiss Prot】：Q9UBF1/O60732 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human MAGC2/MAGC1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Verified picture:
Immunohistochemistry of paraffin-embedded human liver cancer with MAGC2/MAGC1 antibody diluted at 1:200.
Immunohistochemistry of paraffin-embedded human testis cancer with MAGC2/MAGC1 antibody diluted at 1:200.