Anti-OTUD3 Polyclonal Antibody - Cy3
Cat: K114919P - Cy3
Summary:
| 【Product name】：Anti-OTUD3 Polyclonal Antibody - Cy3 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23252 | 【Swiss Prot】：Q5T2D3 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human OTUD3 | |
| 【Public Immunogen Range】：1-178aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains (PubMed:23827681, PubMed:35675826).Important regulator of energy metabolism. Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation. In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation (PubMed:35675826).
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