Anti-GZMB/GZMH Polyclonal Antibody - SAlexa Fluor 594
Cat: K114964P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-GZMB/GZMH Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：3002/2999 | 【Swiss Prot】：P10144/P20718 |
| 【Observed】：32kDa | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human GZMB/GZMH | |
| 【Public Immunogen Range】：80-130/247aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the granzyme subfamily of proteins，part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease，which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins，and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.
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