Anti-PRAME Polyclonal Antibody
Cat: K115012P
Summary:
| 【Product name】：Anti-PRAME Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：23532 | 【Swiss Prot】：P78395 |
| 【Observed】：61kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human PRAME | |
| 【Public Immunogen Range】：459-509/509aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues，except testis. The encoded protein acts as a repressor of retinoic acid receptor，and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Verified picture: