Anti-PRAME Polyclonal Antibody - RBITC
Cat: K115012P - RBITC
Summary:
| 【Product name】：Anti-PRAME Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：23532 | 【Swiss Prot】：P78395 |
| 【Observed】：61kDa | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human PRAME | |
| 【Public Immunogen Range】：459-509/509aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues，except testis. The encoded protein acts as a repressor of retinoic acid receptor，and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
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