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Anti-FCAR Polyclonal Antibody - SAlexa Fluor 488
Cat: K115062P - SAlexa Fluor 488
Summary:
【Product name】:Anti-FCAR Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2204 【Swiss Prot】:P24071
【Observed】:62kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human FCAR
【Public Immunogen Range】:20-180aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils; monocytes; macrophages; and eosinophils; where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes; including phagocytosis; antibody-dependent cell-mediated cytotoxicity; and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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