Anti-NAE1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K115188P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-NAE1 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：8883 | 【Swiss Prot】：Q13564 |
| 【Observed】：61kDa | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human NAE1 | |
| 【Public Immunogen Range】：185-534aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties，and it is thought to play a role in the pathogenesis of Alzheimer’s disease. In addition，the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8，a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
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