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Anti-NAE1 Polyclonal Antibody - Cy3
Cat: K115188P - Cy3
Summary:
【Product name】:Anti-NAE1 Polyclonal Antibody - Cy3 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:8883 【Swiss Prot】:Q13564
【Observed】:61kDa
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human NAE1
【Public Immunogen Range】:185-534aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties,and it is thought to play a role in the pathogenesis of Alzheimer’s disease. In addition,the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8,a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
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