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Anti-HAT1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K115210P - SAlexa Fluor 405
Summary:
【Product name】:Anti-HAT1 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8520 【Swiss Prot】:O14929
【Observed】:50kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000.IHC 1:50-200.
【Immunogen】:Recombinant protein of human HAT1
【Public Immunogen Range】:156-334aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones,which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation,particularly of histone H4,plays an important role in replication-dependent chromatin assembly. Specifically,this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12,and to a lesser degree,histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
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