Anti-GADD45A Polyclonal Antibody
Cat: K115262P
Summary:
| 【Product name】：Anti-GADD45A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1647 | 【Swiss Prot】：P24522 |
| 【Observed】：21kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human GADD45A | |
| 【Public Immunogen Range】：1-165aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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