Anti-RELA Polyclonal Antibody - SAlexa Fluor 532
Cat: K115281P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-RELA Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5970 | 【Swiss Prot】：Q04206 |
| 【Observed】：62kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：A synthetic peptide of human RELA | |
| 【Public Immunogen Range】：501-551/551aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor，NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL，RELA，or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene，RELA. Four transcript variants encoding different isoforms have been found for this gene.
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