Anti-ARG1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K115303P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-ARG1 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：383 | 【Swiss Prot】：P05089 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human ARG1 | |
| 【Public Immunogen Range】：200-250/322aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution，subcellular localization，immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene，is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia，an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
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