Anti-CNOT7 Polyclonal Antibody - SAlexa Fluor 660
Cat: K115372P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-CNOT7 Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：29883 | 【Swiss Prot】：Q9UIV1 |
| 【Observed】：33kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human CNOT7 | |
| 【Public Immunogen Range】：1-285aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene binds to an anti-proliferative protein，B-cell translocation protein 1，which negatively regulates cell proliferation. Binding of the two proteins，which is driven by phosphorylation of the anti-proliferative protein，causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.
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