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Anti-CRADD Polyclonal Antibody - SAlexa Fluor 555
Cat: K115384P - SAlexa Fluor 555
Summary:
【Product name】:Anti-CRADD Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8738 【Swiss Prot】:P78560
【Observed】:23kDa
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human CRADD
【Public Immunogen Range】:1-199aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex,which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase,and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
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