Anti-TIMM8A Polyclonal Antibody
Cat: K115388P
Summary:
| 【Product name】：Anti-TIMM8A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1678 | 【Swiss Prot】：O60220 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human TIMM8A | |
| 【Public Immunogen Range】：1-98aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome;an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein，along with TIMM13，forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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