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Anti-ACTR1B Polyclonal Antibody - SAlexa Fluor 350
Cat: K115423P - SAlexa Fluor 350
Summary:
【Product name】:Anti-ACTR1B Polyclonal Antibody - SAlexa Fluor 350 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10120 【Swiss Prot】:P42025
【Observed】:49kDa
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human ACTR1B
【Public Immunogen Range】:10-270aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a 42.3 kD subunit of dynactin,a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions,including ER-to-Golgi transport,the centripetal movement of lysosomes and endosomes,spindle formation,chromosome movement,nuclear positioning,and axonogenesis. This subunit,like ACTR1A,is an actin-related protein. These two proteins,which are of equal length and share 90% amino acid identity,are present in a constant ratio of approximately 1:15 in the dynactin complex.
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