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Anti-PIK3C2A Polyclonal Antibody - Cy5
Cat: K115474P - Cy5
Summary:
【Product name】:Anti-PIK3C2A Polyclonal Antibody - Cy5 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5286 【Swiss Prot】:O00443
【Observed】:190kDa
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human PIK3C2A
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation,oncogenic transformation,cell survival,cell migration,and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain,a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes,and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
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