Anti-GDF9 Polyclonal Antibody
Cat: K115642P
Summary:
| 【Product name】：Anti-GDF9 Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2661 | 【Swiss Prot】：O60383 |
| 【Observed】：Baboon | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human GDF9 | |
| 【Public Immunogen Range】：250-300/454aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates ovarian function. Reduced expression of this gene may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with GDF9 antibody diluted at 1:100.