Anti-PFKM Polyclonal Antibody
Cat: K115980P
Summary:
| 【Product name】：Anti-PFKM Polyclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5213 | 【Swiss Prot】：P08237 |
| 【Observed】：Bovine;Rabbit;Pig;;Horse | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human PFKM | |
| 【Public Immunogen Range】：60-360aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Three phosphofructokinase isozymes exist in humans: muscle， liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase， which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1，6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII， also known as Tarui disease. Alternatively spliced transcript variants have been described.
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