Anti-TRIM5 Polyclonal Antibody - Cy3.5
Cat: K116002P - Cy3.5
Summary:
| 【Product name】：Anti-TRIM5 Polyclonal Antibody - Cy3.5 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：85363 | 【Swiss Prot】：Q9C035 |
| 【Observed】：Bovine | |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TRIM5 | |
| 【Public Immunogen Range】：41-230aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains， a RING， a B-box type 1 and a B-box type 2， and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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