Anti-PAM16 Polyclonal Antibody - SAlexa Fluor 750
Cat: K116019P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-PAM16 Polyclonal Antibody - SAlexa Fluor 750 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51025 | 【Swiss Prot】：Q9Y3D7 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human PAM16 | |
| 【Public Immunogen Range】：11-125aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia， an early lethal skeletal dysplasia characterized by short stature， developmental delay and other skeletal abnormalities.
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