Anti-PAM16 Polyclonal Antibody - SAlexa Fluor 647
Cat: K116019P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-PAM16 Polyclonal Antibody - SAlexa Fluor 647 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51025 | 【Swiss Prot】：Q9Y3D7 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PAM16 | |
| 【Public Immunogen Range】：11-125aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia， an early lethal skeletal dysplasia characterized by short stature， developmental delay and other skeletal abnormalities.
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