Anti-NALP3/CIAS1 Polyclonal antibody
Cat: K011445P
Summary:
| 【Product name】：Anti-NALP3/CIAS1 Polyclonal antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：114548 | 【Swiss Prot】：Q96P20 |
| 【Observed】：Mouse | |
| 【Tested applications】：IHC,FCM,IF,WB,ELISA | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:100-500.FCM 1ug/Test.IF 1:100-500.ELISA 1:5000-10000. | |
| 【Immunogen】：A synthetic peptide of human NALP3/CIAS1 | |
| 【Public Immunogen Range】：551-630/1036aa | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
May function as an inducer of apoptosis.Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling.Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65.Also inhibits transcriptional activity of RELA.Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.Subcellular Location : Cytoplasm.
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