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Anti-F4/80 Polyclonal Antibody - Biotin
Cat: K011461P - Biotin
Summary:
【Product name】:Anti-F4/80 Polyclonal Antibody - Biotin
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:13733 【Swiss Prot】:Q61549
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of mouse F4/80
【Public Immunogen Range】:443-644aa
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
Mouse F4/80 also named as EMR1 and Gpf480 is a 160-kDa cell surface glycoprotein which is a member of the EGF TM7 family.The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues including Kupffer cells in liver splenic red pulp macrophages brain microglia gut lamina propria and Langerhans cells in the skin.The function of F4/80 is unclear but it is speculated to be involved in macrophage adhesion events cell migration or as a G protein-coupled signaling component of macrophages.
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