Anti-F4/80 Polyclonal Antibody - SAlexa Fluor 488
Cat: K011461P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-F4/80 Polyclonal Antibody - SAlexa Fluor 488 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：13733 | 【Swiss Prot】：Q61549 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of mouse F4/80 | |
| 【Public Immunogen Range】：443-644aa | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
Mouse F4/80 also named as EMR1 and Gpf480 is a 160-kDa cell surface glycoprotein which is a member of the EGF TM7 family.The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues including Kupffer cells in liver splenic red pulp macrophages brain microglia gut lamina propria and Langerhans cells in the skin.The function of F4/80 is unclear but it is speculated to be involved in macrophage adhesion events cell migration or as a G protein-coupled signaling component of macrophages.
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