Background:
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan.Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core which may be important for neutralizing hydrolytic enzymes.This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin which may serve as a mediator of granule-mediated apoptosis.Two transcript variants only one of them protein-coding have been found for this gene.