Anti-Phospho-AMPKa1(T183)/AMPKa2(T172) Polyclonal Antibody - Cy3.5
Cat: K011473P - Cy3.5
Summary:
| 【Product name】：Anti-Phospho-AMPKa1(T183)/AMPKa2(T172) Polyclonal Antibody - Cy3.5 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5563 | 【Swiss Prot】：P54646 |
| 【Tested applications】：ELISA,WB | |
| 【Recommended dilution】：WB 1:500-1000.ELISA 1ug/ml. | |
| 【Immunogen】：A synthetic peptide of human Phospho-AMPKa1(T183)/AMPKa2(T172) | |
| 【Public Immunogen Range】：767-1116aa | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene belongs to the ser/thr protein kinase family.It is the catalytic subunit of the 5’-prime-AMP-activated protein kinase (AMPK).AMPK is a cellular energy sensor conserved in all eukaryotic cells.The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio.AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation.It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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