Anti-RAGE Monoclonal Antibody
Cat: K011505M
Summary:
| 【Product name】：Anti-RAGE Monoclonal Antibody | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：177 | 【Swiss Prot】：Q15109 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-1000. | |
| 【Immunogen】：A synthetic peptide of human RAGE | |
| 【Public Immunogen Range】：135-484aa | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
The receptor for advanced glycation end products (RAGE) is member of the immunoglobulin (Ig) superfamily.Mediates interactions of advanced glycosylation end products (AGE).Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB.Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase which leads to activation of transcription.
Verified picture: