Anti-SPP1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K011508P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-SPP1 Polyclonal Antibody - SAlexa Fluor 488 | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：20750 | 【Swiss Prot】：P10923 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human SPP1 | |
| 【Public Immunogen Range】：221-280/294aa | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine.Osteopontin is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite.It is also involved in the anchoring of osteoclasts to the mineral of bone matrix via the vitronectin receptor which has specificity for osteopontin.Osteopontin is overexpressed in a variety of cancers including lung breast colorectal stomach ovarian melanoma and mesothelioma.
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