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Anti-Phospho-AMPKα1-(T183)+AMPKα2-(T172)Monoclonal Antibody - Cy5.5
Cat: K011515M - Cy5.5
Summary:
【Product name】:Anti-Phospho-AMPKα1-(T183)+AMPKα2-(T172)Monoclonal Antibody - Cy5.5
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5563 【Swiss Prot】:P54646
【Observed】:Mouse;Rabbit;Sheep;Chicken
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human Phospho-AMPKα1-(T183)+AMPKα2-(T172)
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene belongs to the ser/thr protein kinase family.It is the catalytic subunit of the 5’-prime-AMP-activated protein kinase (AMPK).AMPK is a cellular energy sensor conserved in all eukaryotic cells.The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio.AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation.It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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