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Anti-UN13D Polyclonal Antibody
Cat: K011519P
Summary:
【Product name】:Anti-UN13D Polyclonal Antibody
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:201294 【Swiss Prot】:Q70J99
【Observed】:Pig;Rabbit;Canine;Chicken;Zebrafish;Duck
【Tested applications】:IF,IHC,WB
【Recommended dilution】:WB 1:500-2000.IHC 1:50-200.IF 1:50-200.
【Immunogen】:Recombinant protein of human UN13D
【Public Immunogen Range】:900-1090aa
【Storage】:Store at -20℃.Avoid freeze/thaw cycles.
Background:
This gene encodes a protein that is a member of the UNC13 family containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins.The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion.Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3 a genetically heterogeneous rare autosomal recessive disorder.[provided by RefSeq Jul 2008]
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