Anti-Ly-6G/Ly-6C(PE) Monoclonal Antibody - RBITC
Cat: K011542M - RBITC
Summary:
| 【Product name】：Anti-Ly-6G/Ly-6C(PE) Monoclonal Antibody - RBITC | |
| 【Isotype】：IgG2b κ | 【Purification】：Affinity purification |
| 【Gene ID】：546644 | 【Swiss Prot】：P35461 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Raised against granulocytes of mouse origin | |
| 【Storage】：Store at 2-8℃ in dark.Do not freeze. | |
Background:
Ly-6G (lymphocyte antigen 6 complex， locus G)， also known as Gr-1， is a 21-25 kDa， glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow (PMID: 8360469). The expression of Ly-6G increases on neutrophils as they differentiate from immature cells in the bone marrow to mature cells in the blood and spleen (PMID: 8890901). Antibodies targeting Ly6G (RB6-8C5 or 1A8) are commonly used in studies aimed at identifying the role of neutrophils (PMID: 23543767). The RB6-8C5 mAb has been reported to cross-react with Ly-6C on cells expressing Ly-6C (PMID: 8360469).
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