Anti-AMACR Monoclonal Antibody - SAlexa Fluor 405
Cat: K000050M - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-AMACR Monoclonal Antibody - SAlexa Fluor 405 | 【Source】：Mouse |
| 【Isotype】：IgG1 | |
| 【Gene ID】：23600 | 【Swiss Prot】：Q9UHK6 |
| 【Species reactivity】：Human,Rat | |
| 【Tested applications】：IF,ICC,WB | |
| 【Immunogen】：Recombinant protein of human AMACR(C-term) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Verified picture: