Anti-ATIC Monoclonal Antibody
Cat: K000068M
Summary:
| 【Product name】：Anti-ATIC Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：471 | 【Swiss Prot】：P31939 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-1000. | |
| 【Immunogen】：Recombinant protein of human ATIC | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Verified picture:
Western blot analysis with ATIC antibody diluted at 1:1000;Lane: Mouse colon A549 A431 LNCAP Jurkat U2OS Rat liver Mouse kidney Mouse brain HeLa.