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Anti-CYP17A1 Monoclonal Antibody
Cat: K000082M
Summary:
【Product name】:Anti-CYP17A1 Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG2b 【Purification】:Affinity purification
【Gene ID】:1586 【Swiss Prot】:P05093
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:Recombinant protein of human CYP17A1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.This protein localizes to the endoplasmic reticulum.It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins,mineralocorticoids,glucocorticoids,androgens,and estrogens.Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency,17-alpha-hydroxylase/17,20-lyase deficiency,pseudohermaphroditism,and adrenal hyperplasia.[provided by RefSeq,Jul 2008]
Verified picture:
Western blot analysis with CYP17A1 antibody diluted at 1:1000;Lane: A549 HepG2 HeLa.