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Anti-PCNA Monoclonal Antibody - Cy7
Cat: K000119M - Cy7
Summary:
【Product name】:Anti-PCNA Monoclonal Antibody - Cy7 【Source】:Mouse
【Isotype】:IgG2b
【Gene ID】:5111 【Swiss Prot】:P12004
【Species reactivity】:Mouse,Rat,Human,Hamster,Monkey
【Tested applications】:ICC,IHC,IF,IP,WB
【Immunogen】:Recombinant protein of human PCNA
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta.The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication.In response to DNA damage,this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.Two transcript variants encoding the same protein have been found for this gene.Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.[provided by RefSeq,Jul 2008]
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