Anti-XRCC6 Monoclonal Antibody
Cat: K000133M
Summary:
| 【Product name】：Anti-XRCC6 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：2547 | 【Swiss Prot】：P12956 |
| 【Tested applications】：ChIP,IP,ICC,WB,IF | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. IP 1:20. ChIP 1:20. ICC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human XRCC6 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Verified picture:
Western blot analysis with XRCC6 antibody diluted at 1:1000;Lane: A549 HeLa COS7 K562.
Immunofluorescence analysis of HeLa using XRCC6 antibody diluted at 1:100.
Immunoprecipitation analysis of HeLa extracts using XRCC6 antibody(IP:1:20;WB:1:1000).Control IgG: Normal Mouse IgG.