Anti-EGFR Monoclonal Antibody - RBITC
Cat: K000138M - RBITC
Summary:
| 【Product name】：Anti-EGFR Monoclonal Antibody - RBITC | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：1956 | 【Swiss Prot】：P00533 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Purified recombinant human EGFR protein fragments expressed in E.coli. | |
| 【Storage】：Store at -20°C. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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