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Anti-XRCC1 Monoclonal Antibody - SAlexa Fluor 660
Cat: K000148M - SAlexa Fluor 660
Summary:
【Product name】:Anti-XRCC1 Monoclonal Antibody - SAlexa Fluor 660 【Source】:Mouse
【Isotype】:IgG1 【Purification】:Affinity purification
【Gene ID】:7515 【Swiss Prot】:P18887
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:Recombinant protein of human XRCC1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents.This protein interacts with DNA ligase III,polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway.It may play a role in DNA processing during meiogenesis and recombination in germ cells.A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.[provided by RefSeq,Jul 2008]
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