Anti-EIF2S1 Monoclonal Antibody - SAlexa Fluor 640
Cat: K000162M - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-EIF2S1 Monoclonal Antibody - SAlexa Fluor 640 | 【Source】：Mouse |
| 【Isotype】：IgG2b | 【Purification】：Affinity purification |
| 【Gene ID】：1965 | 【Swiss Prot】：P05198 |
| 【Tested applications】：ICC,IP,IF,WB | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. IP 1:20. ICC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human EIF2S1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).
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