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Anti-LMNB1 Monoclonal Antibody
Cat: K000167M
Summary:
【Product name】:Anti-LMNB1 Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG2b 【Purification】:Affinity purification
【Gene ID】:4001 【Swiss Prot】:P20700
【Tested applications】:ICC,IF,WB
【Recommended dilution】:WB 1:500-1000. IF 1:100-200. ICC 1:50-200.
【Immunogen】:Recombinant protein of human LMNB1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010]
Verified picture:
Western blot analysis with LMNB1 antibody diluted at 1:1000;Lane: COS7 Molt4 A549 3T3.
Immunofluorescence analysis of HeLa using LMNB1 antibody diluted at 1:100.