Anti-CTNNB1 Monoclonal Antibody
Cat: K000226M
Summary:
| 【Product name】：Anti-CTNNB1 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Saturated ammonium sulfate precipitation |
| 【Gene ID】：1499 | 【Swiss Prot】：P35222 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-2000. IHC 1:200-500. | |
| 【Immunogen】：Recombinant Protein | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
Verified picture:
Western blot analysis with CTNNB1 antibody diluted at 1:2000 , lane1-4: Hela, 293T, Mouse Liver Tissue, Rat Liver Tissue
Immunohistochemistry of paraffin-embedded Human Lung cancer with CTNNB1 antibody diluted at 1:500