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Anti-BMP2 Polyclonal Antibody - SAlexa Fluor 660
Cat: K000320P - SAlexa Fluor 660
Summary:
【Product name】:Anti-BMP2 Polyclonal Antibody - SAlexa Fluor 660 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:650 【Swiss Prot】:P12643
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IHC,WB
【Immunogen】:Recombinant protein of human BMP2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
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