Anti-SOX2 Polyclonal Antibody
Cat: K000326P
Summary:
| 【Product name】：Anti-SOX2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6657 | 【Swiss Prot】：P48431 |
| 【Tested applications】：WB,IP,IF,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human SOX2 | |
| 【Public Immunogen Range】：1-140aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Verified picture:
Immunohistochemistry of paraffin-embedded rat brain using SOX2 antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using SOX2 antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis using SOX2 antibody.
Western blot analysis with SOX2 antibody diluted at 1:1000;Lane: MCF7 cells.
Immunohistochemistry of paraffin-embedded mouse embryos with SOX2 antibody diluted at 1:100.
Immunofluorescence analysis of F9 cells using SOX2 antibody diluted at 1:100.